Zodiakos, trained by Roger Fell and ridden by Jimmy Sullivan, created history as the first winner on British horse racing’s resumption after a 76-day break because of coronavirus.
The Newcastle card was the first since the UK government cleared the sport to resume, subject to guidelines.
The 22-1 chance edged out stablemate Al Ozzdi, the mount of champion all-weather jockey Ben Curtis.
“That has blown away the cobwebs,” Sullivan said afterwards.
“It was hard work from about three and a half furlongs out but he galloped well and Roger had him spot on.
“The ground is very hard and it played to his strengths at the end. Al Ozzdi got past me but in the last 100 yards my horse’s stamina kicked in.”
The Newcastle meeting features a 10-race card with a maximum of 12 runners in each race.
Those attending had to complete a three-stage screening process, including medical checks before departure and on arrival.
Strict hygiene and social distancing protocols were in place with face coverings required by certain groups, including jockeys and stalls handlers, which was a new experience for winning jockey Sullivan.
“In this heat today, riding in the mask, it is very warm and after pulling up, I pulled it down a little just to get a few breaths in,” he admitted.
“It wasn’t too bad, though, it’s manageable and it’s the sort of thing that in a week you won’t even notice it.”