The minute-long clip shows chaos descending at the food chain in Grand Central, Stockport as two groups of yobs are seen rioting.
At one point, one female is hit round the face with a cleaning mop as she confronts one of the men.
Staff seem shocked and powerless to intervene as the feud unfolded at 05:30 on Sunday.
The clip begins during the middle of the altercation and it is not clear how the dispute began.
The fight broke out inside the McDonald's on Sunday
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There were six or seven brawling in their kitchen
Michael Taylor, eyewitness
In the footage, the unruly groups are seen behind the McDonalds cash desk as scuffles break out all around.
At one point, two people can be seen pinning a man to the food counter while throwing punches at the back of his head.
Another can be heard shouting “f****** kill him” as a woman retaliates to being hit in the face with a mop.
The fight spilled into the kitchen area at the fast-food restaurant
The mass-scuffle was uploaded to Facebook by officer worker Michael Taylor.
The 27-year-old, who had been out celebrating a friend’s 30th birthday said he was “disgusted” by what he had seen.
“There was no security on the door so what were the staff supposed to do?” he told Manchester Evening News.
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Greater Manchester Police confirmed it had attended the scene
“There were six or seven brawling in their kitchen. I felt sorry for them. It was a disgrace and they shouldn’t have to put up with it," he continued.
“We were queuing up to get our food. It came out of nowhere. They just started firing off and they ended up in the kitchen. It was mental.
“Although it wasn’t caught on film, at one point one guy picks up a cheese burger and then launches it at someone, saying ‘have a f***ing cheeseburger you d***’.”
Greater Manchester Police confirmed it had been called to the restaurant in Wellington Road South.
A spokesman said a 24-year-old man had been arrested on suspicion of assault and violent disorder.
A McDonald's spokesman said non of its staff were hurt
A McDonalds spokesman said: “We can confirm an incident occurred at our Stockport Forum restaurant in the early hours of Sunday morning.
"Police were called and alerted to this disturbance and visited the restaurant which was closed for a short time to allow the police to investigate.
"Our primary concern is for our staff and other customers who were unhurt during this incident."
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