The 31-year-old model fell heavily during training of the Channel 4 skiing series yesterday and was left with severe damage to her knee.
It's believed that the estranged wife of Brian McFadden suffered the fall while practising for the Ski Cross – a race which sees celebrities race down a track at speeds of up to 75mph.
Despite being known for causing a number of celebrity injuries, Vogue insisted she would be back to compete on the show next year if it is commissioned for another series.
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Vogue Williams has been forced to pull out of The Jump after seriously damaging her knee
Vogue was reportedly one of the frontrunners to win this year's series
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The Jump celebrity injuries
Really disappointed to be out of The Jump.
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"Really disappointed to be out of The Jump. I've had the time of my life and if the show is back next year I'll be in it to win it! @Channel4," she wrote on Twitter.
Meanwhile, her spokesperson told Express.co.uk: "Unfortunately Vogue had a fall during a ski cross training session for The Jump and injured her knee, which means she will be unable to compete in the live shows starting this Sunday.
"It's a real shame as I know Vogue was having such a brilliant time. She is obviously gutted to be missing out on the full competition but we all knew the risks involved when she signed up and that these kind of things could happen."
Vogue made the announcement on Twitter earlier this evening
Vogue has vowed to compete in the The Jump next year if it returns
It's claimed that Vogue will now be replaced by I'm A Celebrity… Get Me Out of Here! beauty Amy Willerton, who is one of several celebrities on standby incase injuries occur.
The ski show is notorious for causing celebrity injuries with Holby City star Tina Hobley suffering "life-changing" injuries and Olympic gymnastics hero Beth Tweddle needing a painful operation to fuse two fractured vertebrae back together.
Paul McCartney's ex-wife Heather Mills also suffered knee ligament damage, while swimmer Rebecca Adlington was left with a dislocated shoulder.
In spite of being described as the "most dangerous" show on television, Vogue affirmed she was aware of the risks when signing up for the show.
The Jump is often described as the 'most dangerous' show on television
She told MailOnline ahead of her venture: "I think people know injuries are a possible outcome of any show but this is a sport show. We all knew what it was going into it and we're really excited to learn new things.
"If you were on your own ski holiday, you'd be quite careful. We have instructors with us all the time we're not allowed ski on our own or do any sport on our own, so we always have someone on the slopes with us.
"We've got physios and medics with the whole time so you know you're being really looked after."