Junior dos Santos and Stipe Miocic are likely to headline UFC 211
Dos Santos and Miocic met at at the top of the bill at UFC on Fox in December 2014, with the former coming out on top by a unanimous decision.
And when UFC heads to Dallas, Texas on May 13 they will come together again with the UFC Heavyweight Championship on the line.
Dos Santos has held the title before, winning it when he beat Cain Velasquez with a stunning 64-second knockout in 2011.
Junior dos Santos is a former heavyweight champion but has been chasing the belt since 2012
However, he lost the rematch a year later and another 10 months after that, each time failing to win back the heavyweight belt.
The Brazilian only fought once in 2016, beating Ben Rothwell in April, but the No 4 ranked contender has nevertheless been given a third title shot against a man he has already beaten.
Since that defeat, Miocic has fought four times and won all of them – the last three haven’t even lasted into the second round.
The American heavyweight, who was a nationally ranked wrestler at university level, won his world title in Brazil last May when he knocked out Fabricio Werdum.
He then successfully defended the belt in his home state of Ohio against Alistair Overeem in September to complete an impressive 2016 campaign.
No other fights are yet confirmed for UFC 211 but Miocic v Dos Santos 2 is expected to be the main event on the night.