Coutinho had been a doubt for visitors after being taken off in the second half of the 2-2 draw with Bournemouth on Wednesday due to illness.
But the Brazilian is fit enough for a place on the bench alongside compatriot Roberto Firmino.
Into the team comes Trent Alexander-Arnold and Ben Woodburn and Joel Matip in a possible 3-4-3 formation.
For Stoke, Mark Hughes makes three changes.
Glen Johnson for Marc Muniesa, Xherdan Shaqiri in for Mame Biram Diouf and Jon Walters for Charlie Adam.
Liverpool manager Jurgen Klopp
— Liverpool FC (@LFC) April 8, 2017
— Stoke City FC (@stokecity) April 8, 2017
Liverpool line-up predicted to face Stoke City
Fri, April 7, 2017
Express Sport predicts who will start for Liverpool in their clash with Stoke City at the bet365 Stadium on Saturday (3pm)
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Who will Jurgen Klopp pick in his Liverpool starting XI against Stoke City?
Liverpool: Mignolet, Clyne, Lovren, Klavan, Matip, Milner, Can, Wijnaldum, Alexander-Arnold, Woodburn, Origi
Subs: Karius, Moreno, Grujic, Sturridge, Firmino, Lucas, Coutinho
Stoke: Grant; Johnson, Shawcross, Martins Indi, Pieters; Shaqiri, Allen, Cameron, Arnautovic; Walters, Berahino
Subs: Given; Muniesa, Whelan, Adam, Diouf, Crouch, Ramadan