Scotland coach Vern Cotter admitted losing captain Greig Laidlaw was a massive blow against France
Scotland had expected a massive physical challenge after France had pushed defending champions England all the way on the opening weekend.
They fought back to 16-16 with tries from Stuart Hogg and Tim Swinson but France's dominance at the scrum and a constant stream of Scottish injuries meant the boot of Camille Lopez could close out the game.
And Cotter revealed that he would be spending much of the next two weeks ahead of their next game against Wales (February 25) nursing his players back from injury.
Six Nations 2017: 10 weird and wonderful highlights from past tournaments
Fri, February 3, 2017
Click through the gallery for some of the most bizarre moments in Six Nations history
1 of 11
Click through the gallery for the most bizarre moments in Six Nations history
"John Hardie and John Barclay have had their head assessments so we'll have to see how they come through their protocols," Cotter said.
"There's bumps and bruises all over – I think Barclay hurt his shoulder as well.
"We're hoping that everyone will be okay for the next one."
Scotland took their biggest blow just before half-time when captain and goal-kicker Greig Laidlaw was forced off the field.
Get Quotes on Home Insurance
The 31-year-old reappeared with crutches and a protective boot on his ankle, sparking fears that he could be out for weeks or even months.
But Cotter wouldn't be drawn into speculation on the extent of the injury, and praised replacement Ali Price who won just his second cap.
Scotland were at times outmuscled by France during their Six Nations clash
"Greig has a big part on the field as captain and half-back," Cotter added.
"Ali played well when he came and the guys adapted behind him again.
"These things do happen and we have trained for it.
John Barclay suffered head and shoulder injuries during the game
"I think there are other things we can look at to improve on."
"It was a physical encounter and quite a few times we came off second best.
"I thought the boys stuck in really well defensively and defended our line well.
"We scored a couple of tries but perhaps at critical times we just weren't accurate enough.
"We'll have a good look at that before we move onto the next game."