Neil Taylor was sent off for a horror tackle on Seamus Coleman
In a tense and disjointed first-half neither side created any real chances.
After the break Gareth Bale had the first real chance of the night, but his 35-yard strike flew past the far post.
The game continued slowly until it burst into life when Neil Taylor was shown a straight red card for a a heavy challenge on Seamus Coleman.
Gareth Bale couldn't find a winner for Wales
Coleman had to be stretchered off with what looked like a serious injury.
Ireland looked to make the extra man count, and went close when James McClean fired towards goal, but his strike crept wide.
But Wales almost snatched a winner when Bale struck form 20 yards, but his shot failed to hit the target.