Barclays boss, Jes Staley, insisted the capital would remain the “financial centre for Europe” even if the UK quits the single market.
Speaking to the BBC, he said: “We’re looking at contingencies right now, we have a subsidiary bank in Ireland, we have a very large operation in Germany.
Barclays boss Jes Staley said the bank was "committed" to London
I believe London will be the financial Europe even without the single market
“So we are looking at what our options are to operate across Europe if we lose the single market because of Brexit.
“But I don’t think any of those plans reflect a dramatic departure from London.”
Mr Staley, who became chief executive in December 2015, said he did not expect any staff changes to be to the detriment of the UK.
The banking chief was speaking after Barclays posted pre-tax profits of £3.23 billion
“I believe London will be the financial Europe even without the single market – we are committed to the UK.”
The former US investment banking giant was speaking as Barclays posted a hike in annual pre-tax profits to £3.23 billion, up from £1.15 billion.
The surge in profits is down to a strong rise in earnings from its investment banking division.
Jes Staley said Barclays would stay in London even if the UK quit the single market
It’s also been helped by a drop in charges relating to previous misconduct such as the misselling of PPI.
The 60-year-old, who has been selling down and offloading unwanted businesses to focus on US and UK operations, said the group had "accomplished a lot in a year".
He added: "We are now just months away from completing the restructuring of Barclays, and I am more optimistic than ever for our prospects in 2017, and beyond."
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The news comes in stark contrast to warnings from the so-called “Project Fear” campaign during last year’s EU referendum, when it was claimed a vote to Leave the Brussels bloc would cause of a mass exodus of financial services in London.
Other giant companies, including Apple, Facebook and Google have also pledged their commitment to a post-Brexit Britain with hundreds of extra jobs expected to be created.