Police found a number of injured people at the scene earlier this evening. They have now been rushed to hospital.
Two police officers were also hurt, although they are not in a serious condition.
Social media users said people had been shot and stabbed.
One person said: “So there's been 3 stabbings and 2 people shot at barking road.”
Another said: “Having to go round a crime scene trying to get home where someone has died (body is covered).What the yell is going on?! #barkingroad”
These comments were not confirmed by police.
Chidi Oti-Obihara, Green Party candidate for East Ham, said in a video taken at the scene: “It’s very painful. It makes everyone here very angry.
“We know that because we don’t have the budget for community policing the police can’t come in and deal with these issues before the point where there’s a tragic death.”
The incident occurred in Barking Road, east London this evening
A huge area was put in lockdown as police investigated the scene.
Cordons were erected at Barking Road, Barking Close, Cumberland Road, New Barn Street and Balaam Street.
A Met Police spokesperson said: “Police were called on Saturday, 3 June shortly before 17:20 hours to reports of a disturbance in Barking Road, E13.
“Officers attended and found a number of people injured.
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“The London Ambulance Service were called and they have taken to hospitals in east London. We await an update on the nature of their injuries and their condition.
“Two officers have also been taken to hospital suffering from minor injuries.”
Police said the incident was not terror related.
This is a developing story, more to follow…