Obama thanked Merkel for her friendship and praised her for her role in world politiics during his period in office.
Obama and Merkel have created a strong bond during the president’s eight years in office.
A statement from The White House said: "The President thanked Chancellor Merkel for her strong, courageous, and steady leadership."
Obama has made his last phone call as President
Michelle Obama also joined her husband in the phone call.
The White House said: “Given their eight years of friendship and partnership, the President noted that it was fitting that his final call with a foreign leader was with Chancellor Merkel, and he wished her the very best going forward.”
Trump will become the President of the US today officially
Angela Merkel in pictures
Tue, November 29, 2016
Angela Merkel has served as German Chancellor since 2005 and Leader of the Christian Democratic Union since 2000. We take a look at her political career in pictures.
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German Chancellor Angela Merkel attends the gala for the 200th anniversary of Werner von Siemens on November 29, 2016 at the historic headquarters of Siemens in Berlin
The pair have forged a strong friendship during their time in office together
He wished her the very best going forward
The White House
Merkel is up for re-election next year and is hoping to keep her position as chancellor.
Unlike Obama, Trump has openly criticised Merkel.
See said that Merkel made a “catastrophic mistake” by taking in hundreds of thousands of refugees from Syria and the Middle East.
The Obamas told Angela Merkel they had appreciated their personal friendship and forging a deeper partnership between Berlin and Washington.