The Blues beat United 4-0 at Stamford Bridge back in October, while they also knocked the Red Devils out of the FA Cup after a 1-0 victory last month.
And they will be looking to make it a hat-trick of wins against Jose Mourinho's side at Old Trafford this weekend.
Marcos Alonso has sent a warning to his Chelsea team-mates ahead of the clash with Man United
But Alonso believes United will be looking for revenge on Sunday (4.00pm).
"It will be tougher this time around," Alonso told the London Evening Standard.
"They are one of the best teams in England, no doubt. It will be a very hard game, even more so after losing twice against us.
"They will give even more to try and beat us.
"We will have to do the same or more than before to get another win.
"They’re playing at Anderlecht tonight but they have a big squad, full of good players.
"They will be hard to beat, no matter who they pick or the fact they’re playing in the Europa League just three days before. We will have to be ready."
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