After a tough start, Mkhitaryan has enjoyed a fine first season at Manchester United.
The Armenia international has established himself as one of the club’s key players both on the wing and in the No 10 role.
But, with the likes of Luke Shaw, Daley Blind and Matteo Darmian struggling, Mourinho has hinted he is willing to play Mkhitaryan at left-back.
“I will use him everywhere I need. I played him left-back [once],” Mourinho said.
Jose Mourinho has hinted at a new role for Henrikh Mkhitaryan
Henrikh Mkhitaryan could be used at left-back
“He is ready, his mentality has changed, his profile of a player does not change, but the mentality and approach changed.
“He is ready to play for us. What we did last weekend is something we will try and do more and more.
“Start with a system, try to surprise the opponent, then the team is ready to go back and to change during the match. You can only do that with maturity, with some work with time and knowledge with what your players can do.
"During the week we trained for both things. I don’t need to change players, just change the roles on the pitch. So, be ready, after five, 10 or 20 minutes we are going to change.
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"We have more and more capacity to try to do these things to try and surprise opponents and create difficulties."
Mkhitaryan starred as United beat Watford 2-0 this afternoon.
Goals from Juan Mata and Anthony Martial ensured the Red Devils climb above rivals Liverpool to fifth in the Premier League table.
Blind started at left-back but there was no place in the squad for Luke Shaw yet again.