Phil Jones is expected to be out for a month after suffering a suspected broken toe
The Manchester United defender picked up the injury after colliding with club team-mate Chris Smalling while on international duty with England.
Jones failed to travel with the England squad yesterday to prepare for tonight's (7.45pm) friendly with Germany in Dortmund.
Phil Jones has been in impressive form for Man United this season
Man United fans react on Twitter as Chris Smalling injures Phil Jones
Wed, March 22, 2017
Manchester United fans are not happy with Chris Smalling after the centre-back injured Phil Jones while on England duty
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Manchester United fans fume at Chris Smalling after he breaks Phil Jones' toe
He was subsequently sent back to Manchester to undergo scans to find out the extent of his injury.
But he looks certain to miss England's 2018 World Cup qualifier against Lithuania as well as a crucial period for United.
England boss Gareth Southgate said: “It happened in training. He took a knock to his foot.
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Phil Jones' injury will come as a blow to Man United boss Jose Mourinho
“He’ll have it looked at and hopefully it will not be too serious.”
Jose Mourinho's side face a run of nine games in April alone that includes a two-legged Europa League quarter-final against Anderlecht and crunch Premier League clashes with Everton, Chelsea and Manchester City.
But Jones will be forced to watch from the sidelines as he looks set to miss out on securing his first international cap for England since 2015 as well as another portion of the season with United through injury.