The 19-year-old defender came on for the final 23 minutes of United’s 4-0 FA Cup fourth round triumph over Wigan yesterday.
Centre-half Tuanzebe replaced Tim Fosu-Mensah in the second half at Old Trafford.
And reliving the short spell, it was the likes of Ander Herrera and others who helped him embed easily.
Once on the pitch, United’s No 38 was able to rely on his team-mates for support.
Axel Tuanzebe made his Manchester United debut against Wigan
Ander came on in midfield and was constantly talking to me and giving me advice
“After you start playing, you just concentrate on your own game,” Tuanzebe told MUTV. “You get a feel for it, get a couple of touches of the ball.
“The older lads were constantly talking to me, Ander came on in midfield and was constantly talking to me and giving me advice.
“It’s good to have that support from experienced first-team players, it drives you on as a youngster and there’s no better feeling."
Manchester United's Ander Herrera helped Axel Tuanzebe through his first Manchester United apperance
Manchester United's FA Cup player ratings against Wigan
Sun, January 29, 2017
Express Sport brings you Manchester United's player ratings from their FA Cup fourth round win over Wigan Athletic
1 of 11
Sergio Romero – 7.1
Jose Mourinho did not require Zlatan Ibrahimovic from the Manchester United bench against Wigan
Before he stepped out too, Zlatan Ibrahimovic also offered words of comfort.
Tuanzebe added: “I was on the touchline and I could hear Zlatan saying ‘keep it simple, keep it simple’, so I wanted to follow his advice.
“I was just waiting for my moment and it finally came. It’s good to have Warren there too, you know. I grew up with him and for him to see me play is also an honour.”
While Ibrahimovic was kept on the Manchester United bench and rested yesterday, he is expected to return to Jose Mourinho’s starting XI for Wednesday’s Premier League clash at home to Hull (8pm).