Even the outgoing Vice President Joe Biden appears unsure of just how to cope with Mr Trump.
Despite Mr Biden saying, during the election campaign, if the pair were in high school he’d “take him behind the gym” over his comments about groping women.
He told the New York Times: “It’s like a Rubik’s cube trying to figure this guy out.
Donald Trump and his wife Melania in Washington
“We have no freakin’ idea what he’s gonna do.”
Mr Trump, according to the Vice President, has caused the Democratic party to try to reposition itself in an attempt to win back voters with the party seemingly divided on what to do.
He said: “We gotta move to the centre, We gotta move to those white guys, We gotta move to those working-class people or We gotta double down on the social agenda.”
Celebrities slamming Donald Trump
Fri, January 20, 2017
From Meryl Streep to George Clooney, here's what the celebrities have to say about President-elect Donald Trump.
1 of 13
Robert De Niro, Cher and Alec Baldwin slam Donald Trump at the We Stand United NYC Rally
While the precise details of what the 45th president will say during his acceptance speech are unknown his spokesman Sean Spicer indicated it will be a “personal and sincere statement about his vision for the country”.
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He said: “He will discuss what it means to be an American, the challenges that we face, as members of the middle class, that they face.
“He’ll talk about infrastructure and education. Our manufacturing base.
Outgoing Vice President Joe Biden addresses the World Economic Forum in Davos
“I think it’s going to be less of an agenda and more of a philosophical document, a vision of where he sees the country, the proper role of government, the role of citizens.”
Part of the liberal response to Mr Trump has been an unfocused attack on the 70-year-old, such as actor Alec Baldwin’s parody he performs on Saturday Night Live.
Thousands turned out to protest in New York for a rally at the Trump International Hotel and Tower and marched a few blocks to voice their concerns.
Revisiting his role on the show, Mr Baldwin told the crowd: “These people are a disgrace, but there is hope.
“Trump and Pence think you’re going to lay down. That’s one thing about New Yorkers: You don’t lay down.”
Over in Washington protestors clashed with police outside a pro-Trump rally using tear gas to quell the crowd.
Actor Alec Baldwin does his Donald Trump parody at a rally in New York
The former Scottish First Minister Alex Salmond, who has had run-ins with Mr Trump in the past, also appeared to be on the back foot during in interview on BBC Radio 4’s current affairs programme Today.
Mr Salmond said: "We will see which Donald Trump turns up at the inauguration – is it going to be the one who says he will bind America together or the one that rages on Twitter at three o'clock in the morning?”
While Mr Salmond remained critical of the incoming president he conceded that while “a lot of people will be very nervous: be expected his inauguration speech to be “a bit more substantial” then his comments on Twitter.
Incoming US President Donald Trump and his wife Melania arrive to a reception and dinner at Union St
Speaking at a concert at the Lincoln Memorial on the eve of his inauguration, Mr Trump told supporters: "We're going to unify our country.
"We're going to make American great for all our people.
"We're going to do things that haven't been done for our country for many, many decades. It's going to change."
President-elect Donald Trump and his wife, Melania, in front of the Lincoln Memorial
Even Labour leader Jeremy Corbyn made some conciliatory remarks about Mr Trump’s election at the time, saying his victory was a product of an “economic system that simply isn’t working for most people”.
He said at the time of Mr Trump’s victory: “Trump’s election is an unmistakable rejection of a political establishment and an economic system that simply isn’t working for most people.
“It is one that has delivered escalating inequality and stagnating or falling living standards for the majority, both in the US and Britain.
“This is a rejection of a failed economic consensus and a governing elite that has been seen not to have listened. And the public anger that has propelled Donald Trump to office has been reflected in political upheavals across the world.”