Leicester City's Riyad Mahrez and Leicester City's Islam Slimani before the match
The Algeria international came on a substitute in Sunday's 4-2 defeat to Everton but returns to the starting line-up this evening.
Captain Wes Morgan misses out through injury with Yohan Benalouane deputising in his place.
Shinji Okazaki starts up front alongside Jamie Vardy.
For Atletico, Diego Simeone has named an unchanged team from the one which drew 1-1 with Real Madrid on Saturday.
Fernando Torres partners Antoine Griezmann in attack.
Dramatic images as Leicester City fans CLASH with police in Madrid Wed, April 12, 2017
Photos and video from Madrid show riot police confronting Leicester fans as blue smoke flares are set off and chants can be heard.
Play slideshow Twitter 1 of 18
Atletico Madrid: Oblak; Juanfran, Godín, Savic, Filipe Luís; Gabi, Koke, Saúl, Carrasco; Griezmann, Torres.
Subs: Moreira, Correa, Cerci, Hernandez, Thomas, Gaitan, Gimenez.
Leicester: Schmeichel; Simpson, Benalouane, Huth, Fuchs, Drinkwater, Ndidi, Mahrez, Albrighton; Okazaki, Vardy.
Subs: Zieler, Chilwell, King, Amartey, Slimani, Gray, Ulloa.
Get Quotes on Home Insurance