Wayne Rooney was left out of the squad to face Leicester with Manchester United claiming that their captain's absence was due to an illness.
Phil Jones also missed out due to injury with Michael Carrick dropping to the bench in place of Juan Mata.
United were held to a frustrating 0-0 draw in the midweek game against Hull leading to Jose Mourinho selecting an attack-minded starting XI against Leicester.
Jose Mourinho wants Manchester United to go on the offensive against Leicester
Juan Mata was chosen in place of Michael Carrick
And the United boss wants to see his forward thinking players take the game to Leicester to close the gap to the top four.
"Phil is injured, nothing really important but impossible to play today, and I prefer to play with Mata and start immediately with one more attacking player," said Mourinho.
"Mata is playing a lot and all the attacking players we do a lot of rotation because we have so many matches and so many options and I have to say I'm really happy with the way they are playing and the team is playing.
Man United fans react to their team to face Leicester City
Sun, February 5, 2017
Express Sport brings you all the best tweets as Manchester United fans react to Jose Mourinho's team to face Leicester City
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Manchester United fans react to Jose Mourinho's team to face Leicester City
Phil Jones missed out due to injury
"Obviously it is important to score goals. We are not scoring goals.
"It is important to get the right decisions we are not getting, but this is football.
"In the match against a good team like leicester we have to think about them because they are a good team, they are not a team to be in the position they are."