Jack Wilshere has suffered a fracture in his left fibula
The England midfielder clashed with Spurs striker Harry Kane and was forced off after 56 minutes.
And scans have now shown the 25-year-old has suffered a hairline fracture in his left fibula, ending his season.
Jack Wilshere has been plagued by injuries throughout his career
An Arsenal club statement read: "We can confirm that Jack Wilshere has suffered a fractured left fibula.
"The midfielder, who is on a season-long loan at AFC Bournemouth, sustained the injury during the Cherries’ Premier League match at Tottenham Hotspur on Saturday.
"X-rays taken after the game were clear, but further scans showed a hairline crack in the fibula.
Tottenham star Harry Kane and Jack Wilshere clash Wed, April 19, 2017
Click to reveal the clearest snaps of the moment Harry Kane and Jack Wilshere clashed
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Click for snaps of the moment Harry Kane broke Jack Wilshere's leg on Saturday
"Jack will undergo further specialist assessments in the forthcoming days to identify more specifics regarding the injury and also to structure a rehabilitation programme.
"It is hoped that Jack will be fit for the start of next season.
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"Everyone at the club wishes Jack a speedy recovery."
Jack WIlshere will miss the remaining five games of the season
Bournemouth boss Eddie Howe added: "It is a big blow to lose Jack.
“We have loved working with him since he arrived at the club last August.
"He has made a huge contribution to our season, both on and off the pitch. We wish him a quick recovery and thank him for his effort and professionalism while he was with us.”