Beppe Grillo's Five Star Movement are surging in the polls
M5S has overtaken the ruling Democratic Party (PD) which has been plagued by divisions and chaos since former prime minister Matteo Renzi quit following a failed referendum on constitutional reform last year.
Now the anti-establishment party – led by comedian and activist Beppe Grillo – could become the latest party to threaten the traditional face of European politics.
An EMG poll shows Mr Grillo’s party taking 30 per cent of the popular vote, with PD three points behind with 27 per cent.
Meanwhile Forza Italia, led by former prime minister Silvio Berlusconi, and the regionalist Northern League party each have a 12 per cent share of the votes.
Renzi's resignation in December has sparked chaos within his party
If Mr Renzi’s prediction that a general election could be held as early as this June, polls suggest M5S could be among the favourites to win.
The party has promised a referendum on membership of the Eurozone and plan on benefiting from the split in the ruling PD and division in the centre-right.
Divisions in PD have grown since the resignation of Mr Renzi in December.
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Geert Wilders wants to 'de-Islamicise' the Netherlands, hopes clashes between Turkish-Dutch protesters and the police, along with Ankara's accusations of Dutch 'fascism', will help bolster his chances of finishing first
After he stood down, Paolo Gentiloni became the new prime minister – but the former PM revealed he would be seeking re-election at a party congress in April or May.
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A boycott was then proposed in protest against the announcement, with former House whip Robert Sperenza and former leader PierLuigi Bersani refusing the attend the event.
While Justice Minister Andrea Orlando and two other members, Gianni Cuperlo and Cesare Damiano, also called on the party to form a new branch "to reform the party”.
Now the PD appears to be paying the price for its internal feuds, as it dropped more than three percentage points in a month.