Sindh Police said a suicide bomber attacked a crowd at Lal Shahbaz Qalandar’s shrine in Jamshoro killing 72 people.
It is believed the attacker made his way onto the site through the shrine’s golden gate before detonating the bomb near a window.
Amaq, Islamic State's news agency, said ISIS have claimed responsibility for the bombing.
Prime Minister Nawaz Sharif immediately condemned what he termed an attack on Lal Shahbaz Qalandar in the town of Sehwan in Sindh province.
Local hospitals have declared an emergency with children thought to be among the wounded.
The shrine was packed with worshippers when the bomb hit.
The past few days have been hard, and my heart is with the victims
Prime Minister Nawaz Sharif
Senior police officer Shabbir Sethar told Reuters from a local hospital that the death toll was likely to rise.
He said: "At least 72 are dead and over 150 have been injured,”
The bombing is the latest in a wave of attacks to rock Pakistan this week. Prime Minister Sharif said: "The past few days have been hard, and my heart is with the victims.
"But we can't let these events divide us, or scare us. We must stand united in this struggle for the Pakistani identity, and universal humanity."
The injured have been rushed to Civil Hospital Jamshoro and People’s Medical Hospital, with at least 15 people said to be in a critical condition.
AFP GETTY/ TWITTER
At least 30 people have died in the suicide bombing at Lal Shehbaz Qalandar's shrine
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Local Dawn TV quoted a medical superintendent identified as Moinuuddin as saying 25 bodies and 25 seriously wounded were brought to a local hospital.
Geo TV quoted an unnamed medical official as saying at least 30 were killed.
Major General Asif Ghafoor, spokesman for Pakistan’s Armed Forces tweeted: “#COAS directed imed assistance to Sehwan blast victims. Army /Rangers moved incl medical support. Hyderabad CMH ready to receive casualties.”
It comes after Pakistani counter-terrorism police raided a militant hideout and killed six suspected members of a Taliban faction that has launched a new campaign of violence against the government, police said on Thursday.
Blast rips through shrine in Pakistan Thu, February 16, 2017
At least 30 people were killed and over 100 others injured when a suspected suicide bomber blew himself up inside the crowded shrine of revered Sufi Lal Shahbaz Qalandar in Sehwan town in Pakistan's Sindh province, the fifth deadly terror attack in the country within a week.
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The shrine of 13th century Muslim Sufi saint Lal Shahbaz Qalandar in Sehwan
Worshippers had crowded into the Lal Shahbaz Qalandar shrine when the bomb went off
A suicide bomber attacked a crowded Sufi shrine
Since Monday, several bomb attacks have hit the country.
The Counter Terrorism Department in Punjab province said its officers surrounded a hideout of the Pakistani Taliban's Jamaat-ur-Ahrar faction in the city of Multan late on Wednesday and ordered the suspects inside to surrender.
The militant faction claimed responsibility for a suicide bomb attack near the Punjab provincial assembly in the city of Lahore on Monday that killed 13 people and wounded more than 80.
Jamaat-ur-Ahrar said the attack was the beginning of a new campaign of violence against the government, security forces, the judiciary and secular political parties.
The bomb ripped through the 13th century Sufi shrine
#COAS directed imed assistance to Sehwan blast victims. Army /Rangers moved incl medical support. Hyderabad CMH ready to receive casualties.
— Maj Gen Asif Ghafoor (@OfficialDGISPR) February 16, 2017
The fight against ISIS Fri, November 18, 2016
The battle against ISIS militants (also abbreviated as Daesh, ISIL, IS and Islamic State) continues in the Middle East.
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Forces battle against ISIS
Since then, militants have killed two bomb-disposal officers in the western city of Quetta and a suicide bomber blew himself up outside a government office near the northwestern city of Peshawar on Wednesday, killing five people.
Hours later suicide bomber on a motor bike attacked a group of judges in a van in Peshawar, killing their driver.
Earlier today, a roadside bomb hit an army convoy, killing three soldiers in the southwestern province of Baluchistan, the military said in a statement. No group claimed responsibility for the attack.
The attacks have underlined the threat militants pose to the government of Prime Minister Nawaz Sharif despite an army offensive launched in 2014 to push them out of their strongholds near the Afghan border.
More to follow…
- Pakistan launch nuke capable missile after successful India test
- GB hands Pakistan an EXTRA £120M in controversial foreign aid scheme
- How safe is it to travel to Pakistan?