The LBC host was taken for a ride as the comedian stormed her show in a bid to lure her “back to humanity”.
Having none of it, Hopkins ordered Russell to leave her studio and after a short showdown the request was honoured and she got her show back.
However, Hopkins was clearly not to be outdone by a comedian so she staged her own coup as payback.
The 42-year-old stormed Brand’s Sunday show and mocked him for being “incompetent”, as well as being “unable” to host his own show.
RADIO X • LBC
Hopkins and Brand hijacked each other’s radio programmes
Claiming a seat in the studio, she said: “You’re incompetent. You talk nonsense and I talk sense. Are these your three monkeys? The three wise monkeys.”
Egging him on, Hopkins asked: “Would you be able to do this show on your own? Do you need sidekicks?”
He retorted: "Don’t be so mean Katie. Let’s cue up All You Need is Love by the Beatles. Come back to humanity Katie Hopkins. It’s not too late for you to be compassionate.
You’re incompetent. You talk nonsense and I talk sense
“We love you Katie, we’re going to spit you back into love. Katie Hopkins is a better woman than when she entered because of the power of love.”
The war for airtime came after Russell charged into the LBC host’s programme just as it was coming to an end.
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Brand, who is hosting a new show on Radio X, caused so much havoc that Hopkins told her producers to cut to the news.
She then began to tell off the eccentric comedian, before ordering him to leave the studio immediately.
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Hopkins said: "Russell Brand, would you mind leaving my studio and I will deal with you after, you naughty child? Have some sense of diplomacy. Poor Paul here was just making an important point."
Mr Brand blamed the prank disruption on a "misunderstanding" before claiming that the LBC host had invited him in.
But Hopkins refused to give in and told her producers: " We are going to the news where you like it or not.
"Russell Brand, out with you!" She later tweeted Mr Brand: "Did you mother never teach you to knock?"