Reading out one shocking post, Holly said: "Sharon…" before she quickly stopped herself from telling the nation the person's full name.
Open-mouthed Holly was then left speechless for a few seconds, before she continued to say of the excuse that the viewer gave: "One day we called in and said we'd both been involved in a car crash on the way to work," as Phillip looked on in shock beside her.
This certainly isn't the first time Holly has made a mistake live on air, with her accidentally sitting on Phillip's lap while hosting the show at the end of last month.
Holly Willoughby almost named and shamed a viewer on today's This Morning
Holly and Phillip Schofield were reading out 'National Sickie Day' tweets
The beauty was attempting to read the auto-cue and sit down on the sofa at the same time, but it was clearly too much for the presenter to handle so early in the morning as she ended up making her way onto her co-host's lap.
Not one to keep the mishap on the down low, Holly squealed and burst out laughing, as she attempted to explain what had happened.
Phillip quipped: "Let me tell you what happened there," as the pair both struggled to get their giggles under control.
This Morning: The funniest moments
Mon, December 12, 2016
This Morning: Laughter, tears and nudity, the most outrageous moments from the ITV show.
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This Morning was thrown into chaos as Holly Willoughby and Gino D'Acampo took on the Christmas cocktail challenge
Holly was left speechless for a few seconds
Holly recently sat on Phillip's lap by accident
Holly then insisted: "I knew the sofa was there," before she added: "I sat down on his lap!"
The much-loved duo then cut to Rylan Clark-Neal who asked what was happening, before he said: "I bet you sat on his lap," with a cheeky smile on his face.
This Morning airs weekdays at 10.30am on ITV.