The tragic phone-in with hosts Holly and Phillip Schofield invited viewers to share their stories about their own experiences having to make unimaginable decisions about their children's health treatment.
Angela described her wish to not resuscitate her son should he suffer from a cardiac arrest, having agreement from the doctors he was seeing.
However, after contracting septicaemia during the final few days of his life, the plans made over the 16 years of his life were scrapped and doctors set about saving his life.
Angela's story reduced the This Morning team to tears with her heartbreaking story
Viewers in Twitter were also devastated by the story
I never had that chance to say goodbye
Angela via This Morning phone in
Holly, 36, was reduced to tears along with Angela upon hearing that the biggest regret is seeing her son after he was made brain dead during the last days of his life.
"He didn't look like our son at that point and I would not want anyone to ever see that," Angela explained.
She continued: "The worst of it was that we were kept separate. And I never had that chance to say goodbye."
As all of the team expressed their apologies for what happened to Angela and her family, viewers took to Twitter to express their heartbreak over the story.
This Morning: Then and Now Mon, May 8, 2017
This Morning presenters then and now: From Holly and Phil to Ruth and Eamonn.
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Phillip Schofield looking fresh-faced in 1985
One posted: "That poor lady on @thismorning my heart is breaking for her. I can understand why Holly is so upset #ThisMorning."
Another added: "That was one of the most awful phone calls they have ever done on #ThisMorning."
A third commented: "#ThisMorning I am in floods of tears also, such a sad story."