Juventus take on Barcelona tonight (7.45pm) in the first leg of their Champions League quarter-final tie.
Higuain is no stranger to Barca, having previously spent six years trying to topple them during his days at Real Madrid.
The Catalan giants came very close to being knocked out by Paris Saint-Germain in the last round of the competition before turning it around with a remarkable 6-1 win in the second leg at the Nou Camp.
Gonzalo Higuain thinks there is a way of beating Barcelona
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We won’t be able to take our foot off the gas, not even for a split-second
And Higuain is under no illusion about the task facing the Binaconeri.
“Football is so changeable, and a team that everyone thought was knocked out went through to the quarters,” Higuain said.
“They’ll be full of confidence. Barca had an off-day in Paris and I don’t think they’ll have another quite like that.
“We have home advantage first and want to get a good result to give ourselves a real chance in Barcelona.
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“We won’t be able to take our foot off the gas, not even for a split-second.”