Groves has fought for a world title three times before and lost all of them, although the September 2015 split decision that went in favour of Badou Jack in Las Vegas is still regarded as controversial.
His most famous world title shots came against Carl Froch in 2013 and 2014 with the rematch at Wembley Stadium drawing 80,000 people to watch live.
Since losing to Jack two years ago, Groves has improved to 28-3, most recently winning tough fights against Martin Murray and Eduard Gutknecht.
But the latter bout left the German in hospital with a bleed in the skull and he has not been able to walk or talk since.
However, the Brit has been encouraged to block the tragedy from his mind when he faces Chudinov, who held and defended the WBA super-middleweight title before losing it to Felix Sturm last year.
What time will George Groves fight Fedor Chudinov?
A packed undercard backs up the IBF welterweight title fight between Brook and Spence Jr in front of the champ’s Sheffield home crowd.
There are 10 bouts scheduled for the evening before the main event with Groves’ world title shot the last of them.
George Groves and Fedor Chudinov will face off ahead of Kell Brook v Errol Spence Jr
George Groves took part in the media workout at Sheffield's Pleasure Gardens yesterday
The action starts from 6pm at Bramall Lane and it is difficult to put an exact time on Groves v Chudinov because of the nature of boxing undercards, the timing of which is notoriously difficult to predict.
However, Brook and Spence Jr are scheduled to walk out to the ring at 10.30pm, which would put the preceding title bout at around 9.30pm.
Will the George Groves v Fedor Chudinov fight be on TV?
As it is part of the Brook v Spence Jr card, the bout will be live on Sky Sports Box Office.
Get Quotes on Home Insurance
Existing customers can book it for £16.95 to watch on their TV or non-Sky customers can sign up for the same price to watch it online.
Who will win George Groves v Fedor Chudinov?
Chudinov is top of the WBA’s super-middleweight rankings with Groves second meaning that outside of the WBA ‘Regular’ champion Tyron Zeuge, this is one of the closest fights in the division.
The bookies have Groves as a strong favourite given his added experience – the Brit has fought 28 times compared to Chudinov’s 15 in the paid ranks.