Jose Mourinho surprised fans by dropping Zlatan Ibrahimovic from the starting line-up for the crunch match against Chelsea.
The 35-year-old admitted after the game against Anderlecht that he was feeling the affects of playing so much football this season – only Paul Pogba has played as many games as Ibrahimovic at United this season.
United still harbour hopes of clinching a top four place but Neville believes Mourinho's squad selection is evidence that he is prioritising the Europa League over the Premier League fight.
Gary Neville believes Jose Mourinho has the Europa League in mind
Zlatan Ibrahimovic was dropped to the bench
"Mourinho said he was going to play a strong side and I think he will argue that he has," Neville told Sky Sports.
"The team is a mixture of preparation for the Europa League match on Thursday but also a tactic that Jose Mourinho believes can be successful against Chelsea, the one they couldn't see off in the FA Cup because of the sending off to Herrera.
"It seems to me that he's going down a similar route.
Manchester United fans fume as Zlatan Ibrahimovic dropped for Chelsea clash Sun, April 16, 2017
Zlatan Ibrahimovic has been dropped to the bench for Manchester United's clash with Chelsea, and fans are livid
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Manchester United fans are livid as Zlatan Ibrahimovic s dropped against Chelsea
"It looks like a counter-attack emphasis with Rashford. Ibrahimovic has played a lot of football and there's no doubt the Europa League is the best chance to qualify for the Champions League with the fixtures they've got coming up.
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"It does look like a team tat will play deeper, may even look like six at the back at times and then try and catch Chelsea on the break.
"But I think if you were Chelsea, you would respond positively to that team, thinking that two of United's best attacking players aren't playing."