The French Open schedule on Wedneday will feature Andy Murray, Rafael Nadal and Novak Djokovic
Djokovic has perhaps the toughest challenge of the four top seeds as he faces Dominic Thiem.
The Austrian is the only man to have beaten French Open favourite Nadal on clay this year – although he was then beaten 6-1, 6-0 by the Serb in the final.
Nadal himself will face a familiar opponent in the shape of fellow Spaniard Pablo Carreno Busta, who at No21 is the lowest ranked player left in the men's draw but shocked Milos Raonic in a five-set epic in the fourth round.
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Those two matches will take place before lunch in Paris with two of the women's quarter-finals – featuring Karolina Pliskova and Simona Halep – splitting them from the other two men's matches of the day.
Murray will be last up on Chatrier, taking on Kei Nishikori who recovered from a first-set bagel against Fernando Verdasco to book his quarter-final slot.
The winner there will play either Wawrinka or Marin Cilic who clash last on Suzanne Lenglen.
Court Philippe Chatrier (10am start BST)
30-Pablo Carreno Busta (Spain) v 4-Rafael Nadal (Spain)
28-Caroline Garcia (France) v 2-Karolina Pliskova (Czech Republic) [NOT BEFORE 1PM]
1-Andy Murray (Britain) v 8-Kei Nishikori (Japan)
Top seed Andy Murray will hope to stamp his authority on the tournament against Kei Nishikori
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Court Suzanne Lenglen (10am start BST)
6-Dominic Thiem (Austria) v 2-Novak Djokovic (Serbia)
5-Elina Svitolina (Ukraine) v 3-Simona Halep (Romania) [NOT BEFORE 1PM]
3-Stan Wawrinka (Switzerland) v 7-Marin Cilic (Croatia)