Speaking at the Ukip spring conference in Bolton, he said Mr Blair, who stated today Brexit could still be blocked, was "yesterday's man".
He furiously tore into the former Labour leader for suggesting British voters didn't realise what they were doing when they voted for the UK to leave the European Union.
Mr Farage said: "Blair is yesterdays man. He’s like the heavyweight world champion who needs to come back and make some money but gets knocked out first round.
"At the end of the day Blair will be on the canvas!"
Nigel Farage tore into Tony Blair today for his Brexit speech
Radical change is coming and it is coming in the course of the next few years
Nigel Farage also warned the political elite more shocks were coming in the next few years.
He said: "I don’t know if 2017 is the year we see dramatic governmental changes in Europe or not.
"But believe me – radical change is coming and it is coming in the course of the next few years."
Nigel Farage warned more huge political shocks were coming
He said issues like immigration which led to Brexit and Donald Trump's US election victory would continue to dictate political results.
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The former Ukip leader said: "People aren’t interested in arguments about the economy, growth…
"People aren’t interested because they don’t believe what they've been told. After our wasn’t our economy meant to fall off a cliff are Brexit?
"People care about national identity, about their community. I would argue people in this country and across the West are beginning to see immigration as a bigger issue than it was even during the referendum. None of this is going away."
Nigel Farage in pictures
Thu, December 15, 2016
Nigel Farage is a British politician who has been the leader of the UK Independence Party since October 2016.
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British politician Nigel Farage arrives at Trump Tower on December 15, 2016 in New York City. President-elect Donald Trump and his transition team are in the process of filling cabinet and other high level positions for the new administration.
He concluded his speech with a plea for support in getting Ukip leader Paul Nuttall elected in next week’s Stoke by-election.
He said: “I do believe we can win this by-election, I do believe we are going to win this by-election
“Please, physically do everything you can to get Paul Nuttall elected as the MP for Stoke Central next Thursday.”
This is an ongoing story. Check back soon for more information.