Spain's Prime Minister Mariano Rajoy's office said the meeting would launch a message of unity
Spanish Prime Minister Mariano Rajoy will be hosting a summit at El Pardo Palace, just outside Madrid, with the leaders of France, Italy, Portugal, Greece, Cyprus and Malta on Monday.
A statement from Mr Rajoy’s office said the meeting will be a chance to "launch a message of unity and commitment to the project of European integration at a decisive moment in our history".
The statement continued: “Europe must continue to work to address the issues of greatest concern to its citizens and strengthen its project of integration.”
France's President Francois Hollande will attend the summit in Madrid
According to the summit agenda, the leaders will meet to discuss the issues of immigration as well as economic, social and defence policies.
The discussion point of immigration is understood to be of particular interest to the southern EU states due to their positioning on the “frontline” of arriving migrants.
The meeting of the leaders will be the third by the group following gatherings in Athens in September and Lisbon in January.
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According to a new index, the EU27 countries fall into three groups: hard-core, hard and soft. These are the countries with the highest scores which indicate a fairly strong opposition to Britain’s position
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France has the highest score in the index at 32.5
Europe must continue to work to address the issues of greatest concern to its citizens and strengthen its project of integration
Statement from Spanish Prime Minister Mariano Rajoy's office
The date of the meeting was announced on March 29 as Britain officially triggered Article 50 to divorce the EU.
A French diplomatic source told the AFP the crisis in Syria will also be discussed.
Last week chemical weapons were reportedly used during an attack in Syria's Idlib province, which killed at least 70 people.
The attack is believed to be carried out by the Syrian President Bashar al-Assad's army, and prompted US President Donald Trump to launch an airstrike on the nation.
Assad’s government has strongly denied any role in the attack.
Italy's Prime Minster Paolo Gentiloni is also expected to attend
Monday’s summit comes as data compiled by the Economist Intelligence Unit revealed nine countries – including three nations whose leaders are meeting today – were classified as being in favour of maintaining a close trade relationship with Britain.
These include Cyprus, Greece, Spain Czech Republic, Denmark, Ireland, Netherlands, Poland and Sweden.
While five countries – Austria, Bulgaria, Croatia, France and Romania – were reportedly strongly against cutting Britain a favourable deal.