England coach Eddie Jones looks set to switch Elliot Daly to full-back for Italy clash
Daly, who scored the 76th-minute try which brought a dramatic victory over Wales in Cardiff, is in line to be moved off the wing to make way for the return of Anthony Watson a week on Sunday at Twickenham, in what could be a glimpse into England's long-term future.
"I want to do something a bit different against Italy. I want to play differently against them; experiment a bit in how we play – and maybe the team might be different," said Jones.
"Elliot has got gas and he has a bit of X Factor about him and that's why we like him. I don't necessarily think wing is his best position.
Anthony Watson looks set to return in Daly's place on the wing at Twickenham
"I want to keep developing the team. My job is to keep doing that. This is all about building a plan for the World Cup and it will be a bit of fun.
"But we've got to win against Italy to win the Six Nations. It's bloody important we beat Italy – and we'll make sure we do. It's a big game for us because we want to take them to the cleaners."
Mako Vunipola is also in line to make his return from a knee injury against the Azzurri if he comes through Saracens' Premiership game at Gloucester on Friday, while clubmate Jamie George could get a rare start at hooker ahead of captain Dylan Hartley.
"Maybe – I'm looking at it all," said Jones, who is also considering moving Owen Farrell to No10 to accommodate a first Test start for Ben Te'o and a first bench involvement for Alex Lozowski.
Mako Vunipola is also in line to return for England against Italy
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Saracens' back-up stand-off, who was a Chelsea football trialist, turned down an approach by Italy to keep his England options open and has caught Jones's eye since being called up to the wider squad.
"I'm so pleased with the way he's going at training for us. He needs some game-time so we'll let him play for his club next week," said Jones, who views Lozowski as a No12 at Test level.
The rest of the England squad will decamp from their normal Surrey base this week to train in central London for a change of scene, with one run out planned for Hyde Park.
"We've got a line-out session," said Jones. "Prince Harry might come out and have a look."