Alex Hales will play no further part in England's one-day tour of India
Hales pulled out of the pre-Christmas tour of Bangladesh and Test matches in India because security concerns.
One-day captain Eoin Morgan also missed the games but both returned to the squad for three ODIs and three T20Is.
But Hales will now fly home after an x-ray today revealed a fracture in his right hand.
The Notts opener had injured his little finger while field during the second ODI which England would eventually lose along and see India take an unassailable 2-0 lead.
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England headed to Sydney with the 2010-11 Ashes in the bag but a series win was at stake. Hundreds from Alastair Cook, Ian Bell and Matt Prior set up a total of 644 before the seamers forced the tourists to an innings win
Hales had treatment after failing to take a catch off MS Dhoni but opened the batting as planned.
However, he made just 14 – adding to his nine in the first ODI – and was at times seen taking his hand off the bat.
And today England's fears were confirmed after scans showed a fractured bone.
Jonny Bairstow and Billings are already in India and one of them will replace Hales in the 12-man squad for the final ODI.
Billings is said to be the favoured candidate having opened in Bangladesh when Jason Roy was injured, although promoting Joe Root or Moeen Ali is also thought to be an option.