Ozil and Sanchez are Arsenal's first and second most expensive signings respectively and have formed an impressive partnership in their time at the Emirates.
Both also remain in talks with the club over new contracts, with just 18 months left on their current deals.
Arsenal stars continue injury comebacks in training
Wed, January 18, 2017
Click through the gallery for the best snaps from Arsenal training
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Click through the gallery for the best snaps of Arsenal training
Ozil has recently returned for illness and in his absence Arsenal won three in four games.
While Sanchez has appeared in every game this season for the Gunners.
Mesut Ozil and Alexis Sanchez are crucial for Arsenal
But Adebayor, who spent three years at the club, believes Arsenal would struggle if they are missing.
He told The Guardian: "Arsenal have a good team but if Sanchez gets injured I don’t know who they’ve got.
Emmanuel Adebayor spent three seasons at Arsenal
"If you look at Chelsea, when Hazard gets injured they’ve got Willian; if Willian gets injured they can still play Moses further forward.
"Arsenal’s problem is that today they are just Ozil and Sanchez. If one of them gets injured, it is a problem."