EasyJet has warned that customer demand for ticket sales for the next six months – which includes the peak summer season – is unexpectedly weak.
The airline blamed uncertainty over the global economy and Brexit for the slowdown in forward bookings.
As a result, EasyJet said it was now more cautious over its outlook for the second half of its financial year.
The airline has already said it expects to make a loss of around £275m for the first half of the year.
EasyJet’s shares fell almost 8% in early trading following the release of its trading update, which had originally been due for release on Friday.
“We are seeing softness in both the UK and Europe, which we believe comes from macroeconomic uncertainty and many unanswered questions surrounding Brexit which are together driving weaker customer demand,” said chief executive Johan Lundgren.
Despite its caution, EasyJet said revenue per seat – a key measure for airlines – would be slightly higher in the second half of the year, while cost per seat would remain flat.
Mr Lundgren said the airline was “operationally well prepared for Brexit”, adding that “whatever happens, we’ll be flying as usual”.
It has established EasyJet Europe, with headquarters in Vienna, which will enable EasyJet to continue to operate flights both across the EU and domestically within EU countries regardless of the Brexit outcome.
Liberum analyst Gerald Khoo said: “The outlook is the challenge, with management having less confidence on the second half – the summer.
“Brexit uncertainty is the main issue, but management sees macro uncertainty beyond the UK too.”
EasyJet’s warning comes amid a tough time for the airline industry, with a combination of factors such as higher fuel bills and excess capacity in the sector contributing to its problems.
Last week, Iceland’s Wow Air collapsed.
Earlier this year, Germany’s Germania filed for bankruptcy, and UK regional airline Flybmi stopped flying in February.
The UK’s struggling Flybe was taken over earlier this month for just one penny a share.
Even giant budget airline Ryanair reported its first quarterly loss since March 2014 last month.