Some viewers are worried that a parallel storyline means more characters lives are at risk in Albert Square.
Last night's episode saw Sylvie Carter (played by Linda Marlow) and her daughters Shirley (Linda Henry) and Tina Carter (Luisa Bradshaw-White) sharing an heartwarming moment together on the tube, a rare setting for EastEnders.
Later, when the dramatic bus crash occurred, the double-decker ploughing into crowds gathered at Bridge Street market, viewers were quick to notice that the out-of-control bus crashed into the railway bridge just moments before.
EastEnders viewers spotted that the bus crashed into the railway bridge moments earlier
EastEnders viewers think Sylvie Carter, Tina Carter and Shirley Carter might be in danger
Changing faces in Eastenders: Can you keep up?
Fri, December 30, 2016
Can you keep up with the young Eastenders who have returned as completely different actors?
1 of 15
Susan Tully played Michelle Fowler until she left for America in 1995, she is now played by Olivier Award-winning actress Jenna Russell
EastEnders fans immediately took to Twitter to voice theories that the fallout from the bus crash would see Sylvie, Shirley and Tina's lives in danger.
One viewer said: "Bus crash into tube bridge with the tube train coming," while another observed: "Now the bus has crashed into the bridge, odds on their being a train crash tomorrow too!?"
BBC bosses have kept tight-lipped over the events in this week's Disaster Week, but viewers are convinced that the suffering is not over for EastEnders.
Although leaked aerial snaps hinted at the bus crash, it's possible that the writers have more disaster still up their sleeve for the Walford residents.
Fans took to Twitter to share their theories
Viewers suspect there may be a second disaster set to hit Albert Square
The horrific bus crash could potentially have left up to 11 of the characters fighting for their lives, when the bus span out of control after the driver appeared to suffer a heart attack.
Eagle-eyed viewers of the episode also spotted a disastrous subtitling error that resulted in Bex Fowler (Jasmine Armfield) being dubbed "a fat desperate sk*t" instead of "a fat desperate little girl".
Fans also slammed the BBC soap for airing the "insensitive" bus crash storyline less than a month after the terrorist attack in Berlin, where a truck was driven intentionally into crowds at a Christmas market, killing 12 people and injuring over 50.