Upset after a testing week of games, 33-year-old Spencer told 30-year-old Heidi that Nicola is “more dead than Kim to me.”
Whispering in bed, Speidi said: “Next nomination, put up Nicola and Coleen. Everyone needs to be up for nomination.”
While taking a bath with 35-year-old Calum Best, 30-year-old Jamie O'Hara revealed that he thinks Spencer and Heidi are using Nicola “as a reason to target” people.
It comes after housemates nominated who they would like to be permanently immune from eviction earlier this week.
Celebrity Big Brother 2017: Speidi crib ‘Nicola McLean is more dead than Kim Woodburn'
Nicola is more dead than Kim to me.
The majority of the house chose James Cosmo for eternal immunity, before he condemned the TV duo to face every public vote.
Nicola was adamant that the 68-year-old should not have picked Speidi, adding that it was the "wrong choice".
In the diary room, James confided in Big Brother, adding: “I just hope it’s not too heated with Heidi and Spencer. The decision I had to make was obviously the wrong one, I didn’t read the situation clearly.
"I thought that they would be absolutely fine with leaving, I’ve got it wrong and apologised. I’m not a realty show player.”
Celebrity Big Brother 2017: Speidi
Celebrity Big Brother 2017: Nicola McLean
Celebrity Big Brother 2017 highlights
Tue, January 17, 2017
Celebrity Big Brother 2017: The best bits from the latest series including all the arguments, kisses and Tony the Pony.
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Celebrity Big Brother viewers were surprised to hear Kim Woodburn urging Chloe Ferry to become an escort
Spencer was annoyed that Nicola, 35, didn’t pick them for eternal immunity and burst out in a rage about James to Heidi, adding: “He’s a f**king piece of sh*t! We’re two different people, I love you, but I’m going to say what I’m going to say!”
Upset about the situation, Nicola darted for the diary room where she told Big Brother: "I feel so bad that I didn’t pick Heidi and Spencer, now they feel like I’m playing a game against them.
"I feel uneasy… I really like them. I don’t know how to play this game, I’m a mess!,” before later adding: "I will never speak to them. They can come to me. I’ve not done anything wrong."
Speaking to Big Brother in the diary room, Spencer and Heidi continued: "Nothing surprising… we always said James C is the biggest player in the house! James C has chinned us! Nicola is now blocked on social media when we get out of here. Gone.”
Celebrity Big Brother continues tonight on Channel 5 at 9pm.