Danny Boyle has praised the EU and insisted Scotland has to leave UK if Brexit goes ahead
Mr Boyle, 60 made the claim while promoting new film T2 Trainspotting in Moscow.
The director, who was widely commended for his work as artistic director of the opening ceremony for the 2012 London Summer Olympic Games, shared some of his thoughts with Russian journalists.
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Mr Boyle, a Manchester-born Englishman, said: "We had our hearts broken with Brexit, because we wanted to stay in the EU.
"Scotland voted for staying in the EU while England voted for Brexit. I think if Brexit still happens, Scotland will leave the United Kingdom."
The opening ceremony for the 2012 London Summer Olympic Games
Mr Boyle adds a growing list of artistic talents to bemoan the democratic vote to leave, including Ewan McGregor, who said he was "angered" following the referendum.
We had our hearts broken with Brexit, we wanted to stay in the EU
The director, who is currently riding high in the box office with the sequel to his original 1996 Edinburgh junkie drama, added the EU had made Scotland a more dynamic and interesting place by bringing in an influx of migrants and students, especially to the capital city Edinburgh.
Government Loses Brexit Vote Appeal Tue, January 24, 2017
Britain's most senior judges ruled that Prime Minister Theresa May does not have the power to trigger the formal process Article 50 for the UK's exit from the European Union without Parliament having a say.
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Issued by the Supreme Court of (top row, from the left) Lord Neuberger, Lord Mance, Lord Kerr, Lord Sumption, (bottom row, from the left) Lady Hale, Lord Clarke, Lord Wilson and Lord Hodge, who agreed with the majority decision that the Government could not trigger Article 50 without Parliamentary approval.
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The director is currently riding high in the box office with the sequel to Trainspotting
As well as the Trainspotting movies, which were based on novels by Scottish author Irvine Welsh, Boyle has directed movies including Shallow Grave, The Beach, 28 Days Later, Sunshine, Slumdog Millionaire, 127 Hours and Steve Jobs.
Scotland's First Minister and SNP leader Nicola Sturgeon is widely expected to announce a second referendum on Scottish independence following the House of Commons' backing of the Brexit Bill.
She is expected to announce her intention to return to the polls at next month's SNP conference with August 2018 tipped as the most likely date for the vote.
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