The party chairman said a series of incidents had led to the decision, and the returning officer for the Stoke-on-Trent Central by-election that Mr Nuttall is standing in has been informed.
Ukip's Paul Oakden said: "Since the address of the house Paul Nuttall has been staying at during the Stoke-on-Trent Central campaign was published on social media there have been a series of concerning incidents at or around it.
"The most serious of these was two unknown men attempting to gain access to the house through a rear entrance.
"There has also been hate mail posted through the letter box and other intrusive behaviour including trespassing in the private garden of the premises and attempts to take pictures through windows and the letterbox."
More to follow…
Ukip leader Paul Nuttall has been forced to flee his home over security fears
Everyone living in the property in Stoke has been forced to leave, not just Mr Nuttall.
A Ukip spokesman told the Express.co.uk that they suspected “politically active” people from outside of Stoke for the disturbances with “groups of youths” congregating outside the house and people trespassing in the garden of the property as well as trying the handle of the front door at the private address.
The spokesman added: “The democratic action and movement of a party cannot operate due to these threats.’
He also confirmed that the police had been informed of events.