Swede Johan Carlsson fired in a pacesetting six-under 66 in the first round of the competition on Thursday.
The 30-year-old picked up five strokes in a blistering outward half of 30 before three back-nine birdies were partially offset by bogeys at the 10th and 18th.
While Carlsson was flying high at the top of the leaderboard, world No9 Justin Rose had to settle for a 72 and fellow Englishman Ian Poulter ballooned to a 76.
The fifth-ranked Henrik Stenson was handily placed on 68, one behind Italy's Francesco Molinari, Kiradech Aphibarnrat of Thailand and Scott Jamieson of Scotland.
Chris Wood is attempting to defend his BMW PGA Championship at Wentworth
BMW PGA Championship latest leaderboard from Wentworth
Keep up with all the action from the second round on Friday with our live updates from Wentworth
BWM PGA Championship 2017 latest updates
2pm: Saturday is traditionally moving day but it looks like there are plenty pulling the trigger early at Wentworth today in glorious sunshine and good scoring conditions.
Belgian Thomas Pieters finished fourth at the Masters earlier this year and has continued his good form.
He shot 68 yesterday and 69 today, leading in the clubhouse on seven under par.
Overnight leader Carlsson is yet to go out but the low rounds of the day so far are 68s from Germany's Maximilian Kieffer and ever-popular Andrew Johnston – or Beef, as he is better known.
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