Devastated Connie Yates and Chris Gard, wept outside the High Court after the ruling
Devastated Connie Yates and Chris Gard wept outside the High Court after a judge sided with Great Ormond Street doctors, ruling they can turn off the baby's life-support machine.
There was a scream of "no" in the court as the decision about eight-month-old Charlie’s care was announced by Mr Justice Francis.
The judge had analysed evidence over three days and had visited the child at Great Ormond Street Hospital.
Giving his ruling, Mr Justice Francis said he had made the decision with the “heaviest of hearts" but with "complete conviction" for Charlie's best interests – adding that he should be able to "die with dignity."
But it has left the baby’s parents struggling to understand why the judge had not “at least given Charlie Gard the chance of treatment”.
The couple’s solicitor Laura Hobey-Hamsher said Charlie’s parents would now “consider what they can do next".
Charlie, who was born on August 4, 2016, has a form of mitochondrial disease
Charlie, who was born on August 4, 2016, has a form of mitochondrial disease, a condition which causes progressive muscle weakness and brain damage.
Specialists at the hospital in London think it is time to stop providing life support treatment for Charlie.
Doctors say the boy, who suffers from a rare genetic condition and has brain damage, should move to a palliative care regime.
But Charlie's parents, who are both in their early 30s, disagree.
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Mr Justice Francis said he had made the decision with the “heaviest of hearts"
Postman Chris and Connie, of Bedfont, west London, want to be allowed to take him to a hospital in the US for a treatment trial.
Doctors in America had offered to try a treatment called nucleoside bypass therapy on Charlie but the judge said experts agreed that the treatment could not reverse Charlie's brain damage.
His parents launched an appeal on the GoFundMe website two months ago, saying they needed £1.2million to fund treatment.
Chris Gard and Connie Yates want to be allowed to take him to a hospital in the US for treatment
They reached their target on Sunday and more than 80,000 people have donated money.
A GoFundMe spokesman said officials will hold discussions with Charlie's parents about what would happen to money raised for treatment.
He said: "We'll be speaking privately to the family in the next few days about what they want to do and how we can support them."
But Mr Justice Francis ruled that life support treatment should stop after analysing evidence at a hearing in the Family Division of the High Court in London.
Doctors at Great Ormond Street are legally allowed to turn off Charlie's life support
The judge said he had decided Charlie should be allowed to die with dignity.
He praised the little boy's parents for their campaign and paid tribute to their devotion.
He said: "It is with the heaviest of hearts, but with complete conviction for Charlie's best interests, that I find it is in Charlie's best interests that I accede to these applications and rule that Great Ormond Street may lawfully withdraw all treatment save for palliative care to permit Charlie to die with dignity.
"I want to thank the team of experts and carers at Great Ormond Street, and others who cannot be named, for the extraordinary care that they have provided to this family.
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"Most importantly of all, I want to thank Charlie's parents for their brave and dignified campaign on his behalf, but more than anything to pay tribute to their absolute dedication to their wonderful boy, from the day that he was born."
He added: “Charlie's parents have, sadly but bravely, acknowledged and accepted that the quality of life that Charlie has at present is not worth sustaining, for he can only breathe through a ventilator.
“And, although they believe that he has a sleep/wake cycle, and can recognise them and react to them when they are close, they realise that he cannot go on as he is.
“He is lying in bed, unable to move, fed through a tube, breathing through a machine. In my full judgement I shall set out more details of his full medical condition."
Ahead of the ruling, Charlie's parents released a statement to their baby son.
It said, in part: "We love you. We will fight for you until the very end and we'll pray that we'll get to hold your warm hand forever. We won't give up on you because you have a rare disease, it's not your fault, you shouldn't have to die."