Cech has missed Arsenal's last three matches after suffering a calf problem against West Brom last month.
Ospina replaced Cech for the 2-2 draw with Manchester City but picked up a knock which led to Martinez playing against West Ham and Crystal Palace.
Arsenal training ahead of Middlesbrough trek Sun, April 16, 2017
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But Cech resumed training last week and Wenger has confirmed the former Czech Republic keeper would be back in the side along with Laurent Koscielny.
"We faced West Brom and Crystal Palace where we had 70 per cent of the ball," he told Arsenal.com.
Petr Cech in training yesterday
"We want to make more with our possession and we also want to be tight at the back.
“The good news is that Laurent Koscielny will come back, Petr Cech will come back into the team, so that’s two experienced players who should help to make it a bit more tranquil and make us a bit more confident.
“When we have possession we need to have a good pace and accuracy, but as well penetration. What we have lacked a little bit is in the final ball because we’ve had many crosses.”
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