Kieran Gibbs comes in at left-back in place of Nacho Monreal.
Hector Bellerin keeps his place in the side after recovering from a concussion suffered last weekend.
Lucas Perez returns to the bench along with Mohamed Elneny, who's back from the Africa Cup of Nations.
— Arsenal FC (@Arsenal) 11 February 2017
Arsenal train ahead of their clash against Hull City
Fri, February 10, 2017
Express Sport brings you all the best snaps as Arsenal train ahead of their clash with Hull
Arsenal FC via Getty Images
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Arsenal train ahead of Hull clash
Hull City boss Marco Silva has brought in Lazar Markovic and Oumar Niasse in place of Evandro & Abel Hernandez.
Michael Dawson misses out with a calf injury picked up in the warm-up before last week's 2-0 Premier League win over Liverpool.
Arsenal boss Arsene Wenger
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Arsenal: Cech, Bellerin, Mustafi, Koscielny, Gibbs, Oxlade-Chamberlain, Coquelin, Walcott, Ozil, Iwobi, Sanchez.
Subs: Ospina, Monreal, Gabriel, Elneny, Lucas, Welbeck, Giroud.
Hull: Jakupovic, Elabdellaoui, Ranocchia, Maguire, Robertson, Huddlestone, N'Diaye, Clucas, Markovic, Grosicki, Niasse.
Subs: Meyler, Maloney, Diomande, Marshall, Elmohamady, Tymon, Evandro.