The Georgia Emergency Management Agency said almost a dozen had died in the southern Cook, Brooks and Berrien counties.
That tornado was one of 16 reported so far this weekend, with 11 of them in Georgia.
Reports have also estimated the state has suffered 100mph winds with flooding taking place in the north of the state.
Eleven tornadoes ripped through Georgia over the weekend
Brooks County Coroner Michael Miller confirmed that two people had been killed in his country which borders Florida with five more in Cook County to the north and four more in Berrien County.
The deaths are on top of the four people that died in the area of Hattiesburg, Mississippi on Saturday morning after a large tornado hit which wrecked homes leaving residents trapped, collapsed buildings and brought down power lines.
Further north in Choctaw County in Mississippi a further four people were injured and at least 20 homes damaged in what the National Weather Service thought could have been a tornado.
A National Weather Service warning of severe weather issued at 3.46am read: ”At 3.45am CST, a confirmed tornado was located over West Hattiesburg, moving northeast at 50 mph.”
Astonishing photos taken at the heart of Tornado Alley
Mon, October 24, 2016
These astonishing photos were taken at the heart of Tornado Alley in the Great Plains of United States of America. Storm Chaser and professional photographer Marko Korosec, 34 from Sezana. Marko often travels to the hurricane hotspot in America a few weeks at a time between May and June when the storms are most severe and the tornado season peaks.
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The tornado situation in the US
National Weather Service Jackson
A tornado struck Richburg
Large parts of the south-eastern US have been hit by storms over the weekend.
The National Weather Service in Atlanta/Peachtree City said a "significant tornado outbreak" was expected on Sunday around the Florida-Georgia border, with storms expected from noon onwards.
It added in a tweet that there had been a large amount of rainfall in the past 24 hours, with the city of Charlotte getting 13.6cm (5.3 inches).
A severe thunderstorm warning is in effect for northwest Florida.
Some 16 tornadoes hit the US over the weekend
Georgia Emergency Management Agency issued advice on the best and worst places to shelter from a tornado late on Saturday in an online video.
It advised locals who found themselves in the path of a tornado to cover themselves with blankets or a mattress for protection.
The safest place to be was in a “basement or interior room, stairwell, or hallway on a low floor” while trying to avoid windows, doors and outside walls.
US state of Georgia struck by tornadoes over the weekend
The tornadoes appear to be moving towards Florida
Meanwhile, new tornado watches have been issued this morning for the Panhandle of Florida and Southern Alabama.
Images on social media showed telephone poles cracked in half, and what looked like entire streets torn apart by the storms that have churned through the South this weekend.